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cell culture 329 human cervical cancer cell lines c 33a  (ATCC)
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329 miltenyi 130 101 506 cd74 apcvio770  (Miltenyi Biotec)
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human epidermoid carcinoma a431 cells  (ATCC)
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breast cancer kinomics  (Kinomics Inc)
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Selected studies of posttranslational modifications
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anti-mouse b220 (apc, pe  (Becton Dickinson)
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Selected studies of posttranslational modifications
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Selected studies of posttranslational modifications
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skbr3 atcc rrid cvcl 0033 human  (DSMZ)
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Selected studies of posttranslational modifications
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bt474 atcc rrid cvcl 0179 human  (DSMZ)
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Selected studies of posttranslational modifications
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human naïve cd4þ t-cell isolation kit  (STEMCELL Technologies Inc)
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Selected studies of posttranslational modifications
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celltiter-glo  (Promega)
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Selected studies of posttranslational modifications
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Image Search Results


Selected studies of posttranslational modifications

Journal: Journal of proteomics

Article Title: Application of Targeted Mass Spectrometry in Bottom-Up Proteomics for Systems Biology Research

doi: 10.1016/j.jprot.2018.02.008

Figure Lengend Snippet: Selected studies of posttranslational modifications

Article Snippet: Breast cancer kinomics Human (MCF-7 breast cancer cell lines) SRM 150 (179) None SIL chemical tag [ 94 ] Cancer Tyr kinomics Human (12 cancer cell lines) PRM 86 (307) None None [ 95 ] Colorectal cancer kinomics Human (HCT116 colorectal cancer cells) PRM 173 (822) None None [ 96 ] Drug-induced phosphorylation Human (5 cell lines) PRM 86 (96) Phosphorylation SPPS [ 92 ] EGF-induced pTyr Human (184A1 mammary epithelial cells) SRM 144 (226) Phosphorylation iTRAQ [ 91 ] Kinome activity during differentiation Human (HeLa, THP-1 cell lines) MS 1 47 (60) Phosphorylation SPPS (pmol/(min*mg protein)) [ 100 ] Kinome activity in cancer Human (14 cell lines, tumor) MS 1 73 (90) Phosphorylation SPPS (pmol/(min*mg protein)) [ 99 ] Kinome activity in cancer Human (9 cell lines) MS 1 73 (90) Phosphorylation SPPS (pmol/(min*mg protein)) [ 98 ] Kinomics Human (12 cell lines) SRM 83 (204) None None [ 44 ] Kinomics Saccharomyces cerevisiae SRM 118 (214) None None [ 201 ] Kinomics of arsenic poisoning Human (GM00637 skin fibroblast cell line) SRM 234 (245) None SILAC [ 202 ] Kinomics of diabetes Human (HEK293T, GM00637 cell lines) SRM 328 (402) None SIL chemical tag [ 203 ] Lung cancer kinomics Human (lung cancer tumor, cells) PRM, SRM 329 (789) None, phosphorylation None [ 97 ] Lung, skin cancer kinomics Human (cancer cells, tumor) SRM 270 (301) None SIL chemical tag [ 93 ] Mitochondrial phosphoproteomics Mouse (heart) SRM 7 (23) None, phosphorylation SPPS [ 204 ] Open in a separate window caption a8 Selected kinomics and phosphoproteomics studies Targeted kinomics has been performed by coupling affinity enrichment of active protein kinases with targeted LC-MS, and this has been used to study breast, colorectal, lung, and skin cancer, as well as diabetes and arsenic poisoning ( ).

Techniques: Isotopic Labeling, Quantitative Proteomics, Phospho-proteomics, Ubiquitin Proteomics, Methylation, Multiplex sample analysis

Selected studies of protein conformation, protein-protein interaction, and cellular components

Journal: Journal of proteomics

Article Title: Application of Targeted Mass Spectrometry in Bottom-Up Proteomics for Systems Biology Research

doi: 10.1016/j.jprot.2018.02.008

Figure Lengend Snippet: Selected studies of protein conformation, protein-protein interaction, and cellular components

Article Snippet: Breast cancer kinomics Human (MCF-7 breast cancer cell lines) SRM 150 (179) None SIL chemical tag [ 94 ] Cancer Tyr kinomics Human (12 cancer cell lines) PRM 86 (307) None None [ 95 ] Colorectal cancer kinomics Human (HCT116 colorectal cancer cells) PRM 173 (822) None None [ 96 ] Drug-induced phosphorylation Human (5 cell lines) PRM 86 (96) Phosphorylation SPPS [ 92 ] EGF-induced pTyr Human (184A1 mammary epithelial cells) SRM 144 (226) Phosphorylation iTRAQ [ 91 ] Kinome activity during differentiation Human (HeLa, THP-1 cell lines) MS 1 47 (60) Phosphorylation SPPS (pmol/(min*mg protein)) [ 100 ] Kinome activity in cancer Human (14 cell lines, tumor) MS 1 73 (90) Phosphorylation SPPS (pmol/(min*mg protein)) [ 99 ] Kinome activity in cancer Human (9 cell lines) MS 1 73 (90) Phosphorylation SPPS (pmol/(min*mg protein)) [ 98 ] Kinomics Human (12 cell lines) SRM 83 (204) None None [ 44 ] Kinomics Saccharomyces cerevisiae SRM 118 (214) None None [ 201 ] Kinomics of arsenic poisoning Human (GM00637 skin fibroblast cell line) SRM 234 (245) None SILAC [ 202 ] Kinomics of diabetes Human (HEK293T, GM00637 cell lines) SRM 328 (402) None SIL chemical tag [ 203 ] Lung cancer kinomics Human (lung cancer tumor, cells) PRM, SRM 329 (789) None, phosphorylation None [ 97 ] Lung, skin cancer kinomics Human (cancer cells, tumor) SRM 270 (301) None SIL chemical tag [ 93 ] Mitochondrial phosphoproteomics Mouse (heart) SRM 7 (23) None, phosphorylation SPPS [ 204 ] Open in a separate window caption a8 Selected kinomics and phosphoproteomics studies Targeted kinomics has been performed by coupling affinity enrichment of active protein kinases with targeted LC-MS, and this has been used to study breast, colorectal, lung, and skin cancer, as well as diabetes and arsenic poisoning ( ).

Techniques: Isotopic Labeling, Quantitative Proteomics, Clinical Proteomics, Multiplex sample analysis, Labeling

Selected kinomics and phosphoproteomics studies

Journal: Journal of proteomics

Article Title: Application of Targeted Mass Spectrometry in Bottom-Up Proteomics for Systems Biology Research

doi: 10.1016/j.jprot.2018.02.008

Figure Lengend Snippet: Selected kinomics and phosphoproteomics studies

Article Snippet: Breast cancer kinomics Human (MCF-7 breast cancer cell lines) SRM 150 (179) None SIL chemical tag [ 94 ] Cancer Tyr kinomics Human (12 cancer cell lines) PRM 86 (307) None None [ 95 ] Colorectal cancer kinomics Human (HCT116 colorectal cancer cells) PRM 173 (822) None None [ 96 ] Drug-induced phosphorylation Human (5 cell lines) PRM 86 (96) Phosphorylation SPPS [ 92 ] EGF-induced pTyr Human (184A1 mammary epithelial cells) SRM 144 (226) Phosphorylation iTRAQ [ 91 ] Kinome activity during differentiation Human (HeLa, THP-1 cell lines) MS 1 47 (60) Phosphorylation SPPS (pmol/(min*mg protein)) [ 100 ] Kinome activity in cancer Human (14 cell lines, tumor) MS 1 73 (90) Phosphorylation SPPS (pmol/(min*mg protein)) [ 99 ] Kinome activity in cancer Human (9 cell lines) MS 1 73 (90) Phosphorylation SPPS (pmol/(min*mg protein)) [ 98 ] Kinomics Human (12 cell lines) SRM 83 (204) None None [ 44 ] Kinomics Saccharomyces cerevisiae SRM 118 (214) None None [ 201 ] Kinomics of arsenic poisoning Human (GM00637 skin fibroblast cell line) SRM 234 (245) None SILAC [ 202 ] Kinomics of diabetes Human (HEK293T, GM00637 cell lines) SRM 328 (402) None SIL chemical tag [ 203 ] Lung cancer kinomics Human (lung cancer tumor, cells) PRM, SRM 329 (789) None, phosphorylation None [ 97 ] Lung, skin cancer kinomics Human (cancer cells, tumor) SRM 270 (301) None SIL chemical tag [ 93 ] Mitochondrial phosphoproteomics Mouse (heart) SRM 7 (23) None, phosphorylation SPPS [ 204 ] Open in a separate window caption a8 Selected kinomics and phosphoproteomics studies Targeted kinomics has been performed by coupling affinity enrichment of active protein kinases with targeted LC-MS, and this has been used to study breast, colorectal, lung, and skin cancer, as well as diabetes and arsenic poisoning ( ).

Techniques: Phospho-proteomics, Isotopic Labeling, Quantitative Proteomics, Multiplex sample analysis, Activity Assay